Is sialylation of IgA the agent provocateur of IgA nephropathy?

Clinical, Histopathological and Immunofluorescent Findings of IgA Nephropathy

Background: IgA nephropathy, a prevalent disease in Asia, is considered the main cause of end stage renal disease among primary glomerular disease. Objective: To determine the frequency of different clinical, histopathological and immunofluorescent characteristics of IgA nephropathy. Methods: Renal biopsies of 376 patients were received for immunofluorescent and for histopathological studies. B...

شیوع نفروپاتی IgA در بیماران مبتلا به گلومرولونفریت اولیه

During a 14-month period (Dec. 1990-Jan. 1992) , renal biopsies were performed on 105 patients with suspected glomerular disease. All specimens were processed for light microscopy (L.M) and immunoflourescence. Work-up revealed 21 patients to suffer a systemic glomerular disease and glomerular disease was found to be primery in 85 cases. Predominant IgG deposition was noted in 71 cases with prim...

Coexistant of Fabry Disease and IgA Glomerulonephritis in a 39 year old male

  Anderson-Fabry disease is a rare inherited X-linked lysosomal storage disease caused by deficiency of the enzyme alpha-galactosidase A. Hereby we report a 39 year old male that presented with proteinuria and edema. Histopathologic, immunofluorescence and ultrastractural examination of renal tissue were in favor  of  Fabry disease in associate with IgA nephropathy. Fabry's disease associated ...

Comment on: Clinical, Histopathological and Immunofluorescent Findings of IgA Nephropathy

IgA Nephropathy and Significance of Immunostaining Data